Bionetic
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Bionetic
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Bionetic
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Saw palmetto (Serenoa repens) berry lipophilic extract is the most extensively studied botanical for benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) in men. Its free fatty acids and phytosterols (beta-sitosterol, campesterol) non-selectively inhibit both 5-alpha reductase isoforms (5AR-1 and 5AR-2) — the enzymes converting testosterone to the more potent DHT that drives prostate epithelial proliferation. Unlike finasteride (which only inhibits 5AR-2), saw palmetto's dual isoform inhibition reduces DHT accumulation in prostate tissue while preserving systemic testosterone. The lipophilic extract at 320 mg daily is the dose validated in the largest double-blind trials and European Medicines Agency (EMA) monograph.
Key Capabilities
Supplement Facts
| Per serving | |
|---|---|
| Saw palmetto berry extract (Serenoa repens) | 160 mg |
Other ingredients: Capsule shell: gelatin; anti-caking agent: magnesium salts of fatty acids; bulking agent: microcrystalline cellulose.
Key Features
Dual inhibitor of 5-alpha reductase isoforms 1 and 2
Reduces DHT accumulation in prostate tissue without lowering testosterone
320 mg lipophilic extract — EMA-validated dose for LUTS support
Improves urinary flow rate and reduces nocturnal urination (nocturia)
Anti-inflammatory via NF-κB inhibition in prostatic epithelium
Validated in multiple double-blind trials for BPH symptom relief
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